FEN1-IN-6

• Target :

  FLAP

• Related Pathways :

  Immunology/Inflammation

• Bioactivity :

  FEN1-IN-6 (compound 9) is a potent Flap endonuclease-1 (FEN1, IC50 = 10 nM) inhibitor, crucial for DNA damage repair in mammalian cells, and also targets the related endonuclease xeroderma pigmentosum G (XPG) with an IC50 of 23 nM [1].

• Smiles :

  S(=O)(=O)(C=1C2=C(SC1)C(=O)N(O)C(=O)N2)C3=CC=CC=C3

• Molecular Formula :

  C12H8N2O5S2

• Molecular Weight :

  324.33

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  824983-84-8