DprE1-IN-9

• Target:

  Others|||Antibacterial

• Related Pathways:

  Others|||Microbiology/Virology

• Bioactivity:

  DprE1-IN-9 (compound B18) is an efficient, reversible inhibitor of DprE1, interacting with the enzyme's receptor cavity. It exhibits potent antimycobacterial properties, demonstrating activity against non-pathogenic H37Ra (MIC=0.18 µg/mL) and pathogenic strains, including H37Rv, as well as clinical MDR and XDR isolates [1].

• Smiles:

  C(N1C=2C(=C(C(NCC(F)(F)F)=O)C=C(C2)C3CC3)OCC1)C=4C(C)=NC(C)=C(C)N4

• Molecular Formula:

  C22H25F3N4O2

• Molecular Weight:

  434.45

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2906099-98-5