CGAS-IN-1

CAT: 0931-T78858-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T78858-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

858770-07-7

Target

CGAS, Others

Related Pathways

Immunology/Inflammation, Others

Bioactivity

CGAS-IN-1 (compound C20), a flavonoid that acts as a Cyclic GMP-AMP Synthase (cGAS) inhibitor, demonstrates IC50 values of 2.28 μM for human cGAS and 1.44 μM for mouse cGAS. By inhibiting the abnormal activation of cGAS linked to numerous immune-mediated inflammatory diseases, cGAS-IN-1 possesses potential anti-inflammatory properties [1].

Smiles

COC1=CC=C2C(OC(=O)C(CCC(=O)N(CC(O)=O)CC(O)=O)=C2C)=C1

Molecular Formula

C18H19NO8

Molecular Weight

377.35

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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CGAS-IN-1

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