CK2-IN-9

• Target:

  Others|||Casein Kinase|||Wnt/beta-catenin

• Related Pathways:

  Stem Cells|||Metabolism|||Others|||Cytoskeletal Signaling

• Bioactivity:

  CK2-IN-9, a potent and selective CK2 kinase inhibitor, exhibits an inhibitory concentration (IC50) of 3 nM against its target enzyme and hampers Wnt reporter activity with an IC50 of 75 nM. In rats, it demonstrates low exposure (AUC=0.36 ?M/h) and high clearance (CL=65 mL/min/kg) [1].

• Smiles:

  C(#N)C1=C2N(C(NC3CC3)=CC(NC4=CC(NC(C)=O)=C(N(CCN(C)C)C)C=C4)=N2)N=C1

• Molecular Formula:

  C23H29N9O

• Molecular Weight:

  447.54

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1461658-58-1