CK2-IN-9

• Target :

  Others|||Casein Kinase|||Wnt/beta-catenin

• Related Pathways :

  Stem Cells|||Metabolism|||Others|||Cytoskeletal Signaling

• Bioactivity :

  CK2-IN-9, a potent and selective CK2 kinase inhibitor, exhibits an inhibitory concentration (IC50) of 3 nM against its target enzyme and hampers Wnt reporter activity with an IC50 of 75 nM. In rats, it demonstrates low exposure (AUC=0.36 ?M/h) and high clearance (CL=65 mL/min/kg) [1].

• Smiles :

  C(#N)C1=C2N(C(NC3CC3)=CC(NC4=CC(NC(C)=O)=C(N(CCN(C)C)C)C=C4)=N2)N=C1

• Molecular Formula :

  C23H29N9O

• Molecular Weight :

  447.54

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1461658-58-1