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CK2-IN-9

CAT: 0931-T78599-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T78599-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1461658-58-1
Target
Others|||Casein Kinase|||Wnt/beta-catenin
Related Pathways
Stem Cells|||Metabolism|||Others|||Cytoskeletal Signaling
Bioactivity
CK2-IN-9, a potent and selective CK2 kinase inhibitor, exhibits an inhibitory concentration (IC50) of 3 nM against its target enzyme and hampers Wnt reporter activity with an IC50 of 75 nM. In rats, it demonstrates low exposure (AUC=0.36 ?M/h) and high clearance (CL=65 mL/min/kg) [1].
Smiles
C(#N)C1=C2N(C(NC3CC3)=CC(NC4=CC(NC(C)=O)=C(N(CCN(C)C)C)C=C4)=N2)N=C1
Molecular Formula
C23H29N9O
Molecular Weight
447.54
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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