Histatin-3

CAT: 0931-T78224-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T78224-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

112844-49-2

Target

Antibacterial

Related Pathways

Microbiology/Virology

Bioactivity

Histatin-3, a 32-amino-acid peptide, exhibits potent antimicrobial activities and serves as a substrate for proprotein convertase 1 (PC1), where it is primarily cleaved at a site carboxy-terminal to Arg25 (HRGYR↓SN) . Additionally, it acts as a moderately potent, reversible, and competitive inhibitor of furin-mediated cleavage of the pentapeptide pGlu-Arg-Thr-Lys-Arg-MCA fluorogenic substrate, with an inhibition constant (Ki) estimated at 1.98 μM [1].

Molecular Formula

C178H258N64O48

Molecular Weight

4062.35

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Histatin-3

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