Histatin 5

• Target :

  MMP

• Related Pathways :

  Proteases/Proteasome

• Bioactivity :

  Histatin 5, a human basic salivary peptide with strong fungicidal properties in vitro, inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 ?M, respectively.

• Smiles :

  [C@@H](CC1=CN=CN1)(NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)NC(CNC([C@H](CC4=CN=CN4)NC([C@H](CC5=CN=CN5)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC6=CN=CN6)NC([C@@H](NC([C@H](CC(O)=O)N)=O)CO)=O)=O)C)=O)CCCCN)=O)CCCNC(=N)N)=O)=O)=O)=O)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCCN)=O)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CC7=CN=CN7)C(N[C@@H](CC8=CN=CN8)C(N[C@H](C(N[C@@H](CC9=CN=CN9)C(N[C@H](C(NCC(N[C@@H](CC%10=CC=C(O)C=C%10)C(O)=O)=O)=O)CCCNC(=N)N)=O)=O)CO)=O)=O)=O)CCCCN)=O)CCC(O)=O)=O

• Molecular Formula :

  C133H195N51O33

• Molecular Weight :

  3036.29

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  115966-68-2