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Skp2 inhibitor 2

CAT: 0931-T78194-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T78194-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2760612-77-7
Target
E1/E2/E3 Enzyme
Related Pathways
Ubiquitination
Bioactivity
Skp2 inhibitor 2 (14f) impedes the F-box protein S-phase kinase-associated protein 2 (Skp2), demonstrating an IC50 of 10.2 μM against Skp2-Cks1. This compound targets Skp2, a component of cullin-RING ligases that recruits and ubiquitinates substrates, playing roles in both proteolytic and non-proteolytic processes [1].
Smiles
O=C(NCC1CCN(C2=NC(C3=CC=CC=C3)=C(N=C2)C=4C=CC=CC4)CC1)C(C)(C)C
Molecular Formula
C27H32N4O
Molecular Weight
428.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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bs-60136C-01SKP2-C25 --- Skp2 Inhibitor
MBS5750404Skp2 Inhibitor C1
MBS5819861Skp2 Inhibitor 2
GTR19238568-01Skp2 inhibitor 3
HY-149293Skp2 inhibitor 1
bs-60137C-01SKPin C1 --- Skp2 Inhibitor
S8652-100mgSkp2 inhibitor C1 (SKPin C1)
MBS130266-01Skp2-Inhibitor-C1. SKPin C1
217795SKP2 E3 Ligase Inhibitor II, SMIP004 (CRL1SKP2 Inhibitor II, p21/Cip1/CKI/Waf1 Activator II, N- (4-Butyl-2-methylphenyl) acetamide, p27/Kip1 Activator II, S-phase Kinase-associated Protein 2 Inhibitor II, SCFSKP2 Inhibitor II, Small Molecule Inhibitor of p27 Depletion 004)
217794SKP2 E3 Ligase Inhibitor I, C1 (p21/Cip1/Waf1 Activator I; p27/Kip1 Activator I, S-phase Kinase-associated Protein 2 Inhibitor I; SCFSKP2 Inhibitor I, CRL1SKP2 Inhibitor I, (Z) -2- (4-Bromo-2- ((4-oxo-3- (pyridin-3-ylmethyl) -2-thioxothiazolidin-5-ylidene) methyl) phenoxy) acetic Acid)

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