Products for Research Use Only

Skp2-IN-4

CAT: 0931-T210947-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T210947-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
E1/E2/E3 Enzyme
Related Pathways
Ubiquitination
Bioactivity
Skp2-IN-4 is an Skp2 inhibitor with an IC50 of 0.38 μM for Skp2-Cks1 binding. It enhances antitumor activity by targeting Skp2, inhibiting tumor proliferation, and inducing S phase cell arrest. Skp2-IN-4 also significantly boosts chemosensitivity to Cisplatin in the NCl-H1299 xenograft mouse model by inhibiting tumor cell stemness, presenting potential for lung and esophageal cancer research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C