PRMT5-IN-25

• Target:

  Histone Methyltransferase

• Related Pathways:

  Chromatin/Epigenetic

• Bioactivity:

  PRMT5-IN-25 (compound 503) is a potent PRMT5 inhibitor with an inhibition constant (K i) of 0.06 nM and demonstrated antiproliferative properties [1].

• Smiles:

  C (N (CC1=CC=C (C (F) (F) F) C=N1) [C@H] (C) C=2N=CC=CN2) (=O) C3=CC4=C (C=C3) N=C (N) C (C) =C4

• Molecular Formula:

  C24H21F3N6O

• Molecular Weight:

  466.46

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2691869-82-4