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PAMP-12 (unmodified)

CAT: 0931-T78027-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T78027-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
929905-12-4
Target
MRGPR
Related Pathways
GPCR/G Protein
Bioactivity
PAMP-12 (unmodified), an endogenous peptide and potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM), induces hypotension by inhibiting catecholamine release from sympathetic nerve endings and adrenal chromaffin cells [1].
Smiles
C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)N)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CC=2C=3C(NC2)=CC=CC3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CO)=O)CC(C)C)=O)C)=O)=O)CCCCN)=O)CC(N)=O)=O)C=4C=5C(NC4)=CC=CC5
Molecular Formula
C77H118N24O15
Molecular Weight
1619.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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