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Deruxtecan analog 2

CAT: 0931-T77816-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T77816-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1599440-10-4
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
Deruxtecan Analog 2 (example 9 P3), a Deruxtecan derivative, serves as an agent-linker conjugate integrating Camptothecin (CPT), a Topo I inhibitor active against colorectal, breast, lung, and ovarian cancers, with a distinct linker. This analog is employed in synthesizing anti-FGFR2 ADC [1].
Smiles
N(C(COCNC(CN)=O)=O)[C@@H]1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6
Molecular Formula
C29H30FN5O7
Molecular Weight
579.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C