TNKS-2-IN-1

CAT: 0931-T77675-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T77675-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

4765-59-7

Target

PARP, Wnt/beta-catenin, Antibiotic

Related Pathways

DNA Damage/DNA Repair, Chromatin/Epigenetic, Cytoskeletal Signaling, Microbiology/Virology, Stem Cells

Purity

0.984

Bioactivity

TNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity against E. coli and S. aureus.TNKS-2-IN-1 inhibits the release of IL-1β from the NLRP3 inflammasome (IC50: 5 μM) by inhibiting IL-1β release from ATP-stimulated J1A.774 cells.

Smiles

[O-][N+](=O)c1ccc(cc1)-c1nc(=O)c2ccccc2[nH]1

Molecular Formula

C14H9N3O3

Molecular Weight

267.24

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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TNKS-2-IN-1

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