LSD1-IN-27

• Target:

  Histone Demethylase|||PD-1/PD-L1

• Related Pathways:

  Cell Cycle/Checkpoint|||Apoptosis|||Immunology/Inflammation|||Chromatin/Epigenetic

• Purity:

  0.9998

• Bioactivity:

  LSD1-IN-27 is a potent LSD1 inhibitor with an IC50 value of 13 nM.LSD1-IN-27 inhibited the stemness and migration of gastric cancer cells.LSD1-IN-27 inhibited the expression of PD-L1 in BGC-823 and MFC cells.LSD1-IN-27 potentiated the T-cell immune response against gastric cancer.

• Smiles:

  N (C=1C2=C (N=C3C1C=C (C) C=C3) C (C) =C (C) C=C2) C4=CC=C (N (C) C) C=C4

• Molecular Formula:

  C24H25N3

• Molecular Weight:

  355.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2904571-94-2