LSD1-IN-27

CAT: 0931-T77635-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T77635-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2904571-94-2

Target

Histone Demethylase, PD-1/PD-L1

Related Pathways

Cell Cycle/Checkpoint, Apoptosis, Immunology/Inflammation, Chromatin/Epigenetic

Purity

0.9998

Bioactivity

LSD1-IN-27 is a potent LSD1 inhibitor with an IC50 value of 13 nM.LSD1-IN-27 inhibited the stemness and migration of gastric cancer cells.LSD1-IN-27 inhibited the expression of PD-L1 in BGC-823 and MFC cells.LSD1-IN-27 potentiated the T-cell immune response against gastric cancer.

Smiles

N(C=1C2=C(N=C3C1C=C(C)C=C3)C(C)=C(C)C=C2)C4=CC=C(N(C)C)C=C4

Molecular Formula

C24H25N3

Molecular Weight

355.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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LSD1-IN-27

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