LSD1-IN-27

• CAS Number :

  2904571-94-2

• Target :

  Histone Demethylase|||PD-1/PD-L1

• Related Pathways :

  Cell Cycle/Checkpoint|||Apoptosis|||Immunology/Inflammation|||Chromatin/Epigenetic

• Purity :

  0.9998

• Bioactivity :

  LSD1-IN-27 is a potent LSD1 inhibitor with an IC50 value of 13 nM.LSD1-IN-27 inhibited the stemness and migration of gastric cancer cells.LSD1-IN-27 inhibited the expression of PD-L1 in BGC-823 and MFC cells.LSD1-IN-27 potentiated the T-cell immune response against gastric cancer.

• Smiles :

  N(C=1C2=C(N=C3C1C=C(C)C=C3)C(C)=C(C)C=C2)C4=CC=C(N(C)C)C=C4

• Molecular Formula :

  C24H25N3

• Molecular Weight :

  355.48

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C