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Nurr1 agonist 2

CAT: 0931-T77549-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T77549-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
742058-34-0
Target
NR4A, Others
Related Pathways
Others, Endocrinology/Hormones
Purity
0.9878
Bioactivity
Nurr1 agonist 2 is a Nurr1 agonist with an EC50 value of 0.07 μM. Nurr1 agonist 2 increases the mRNA expression of the Nurr1-regulated genes tyrosine hydroxylase (TH) and vesicular amino acid transporter 2 (VMAT2) . Nurr1 agonist 2 binds to the recombinant Nurr1 ligand-binding domain (LBD) with a Kd of 0.14 μM. Nurr1 agonist 2 can be used to study parkinsonism.
Smiles
C(O)(=O)C=1SC(=CC1)C2=CC=C(OCC3=CC=CC=C3)C=C2
Molecular Formula
C18H14O3S
Molecular Weight
310.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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