Jatrorrhizine hydroxide

• Target :

  Cholinesterase (ChE) |||5-HT Receptor|||Antibacterial

• Related Pathways :

  Neuroscience|||Microbiology/Virology|||GPCR/G Protein

• Purity :

  0.9999

• Bioactivity :

  Jatrorrhizine hydroxide is an alkaloid extracted from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial, and antioxidant activities. Jatrorrhizine hydroxide is a potent and orally active acetylcholinesterase inhibitor (IC?? = 872 nM) with over 115-fold selectivity over BuChE. Jatrorrhizine hydroxide reduces serotonin and norepinephrine uptake by blocking dopamine uptake-2 transporters.

• Smiles :

  [OH-].OC=1C=C2C(=CC1OC)C=3C=C4C=CC(OC)=C(OC)C4=C[N+]3CC2

• Molecular Formula :

  C20H21NO5

• Molecular Weight :

  355.38

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  483-43-2