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Methdilazine

CAT: 0931-T75313-02Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T75313-02Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1982-37-2
Target
Histamine Receptor, Others, Antibiotic, Antibacterial
Related Pathways
GPCR/G Protein, Immunology/Inflammation, Others, Microbiology/Virology, Neuroscience
Bioactivity
Methdilazine, an orally active (histamine antagonist) antibiotic, demonstrates the ability to inhibit various mycobacteria with minimum inhibitory concentration (MIC) values ranging from 5-15 μg/mL both in vitro and in vivo. This efficacy positions it as a valuable compound for infectious disease research [1] [2].
Smiles
C(N1C=2C(SC=3C1=CC=CC3)=CC=CC2)C4CN(C)CC4
Molecular Formula
C18H20N2S
Molecular Weight
296.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Methdilazine

Methdilazine is a phenothiazine substituted on nitrogen by a (1-methylpyrrolidin-3-yl)methyl group; a first-generation antihistamine with anticholinergic properties. It has a role as a histamine antagonist, a cholinergic antagonist and an antipruritic drug. It is a member of phenothiazines and a N-alkylpyrrolidine.

CAS Number1982-37-2
PubChem CID14677
IUPAC Name10-[(1-methylpyrrolidin-3-yl)methyl]phenothiazine
Molecular FormulaC18H20N2S
Molecular Weight296.4
XLogP5.2
Topological Polar Surface Area31.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Heavy Atom Count21
Formal Charge0
Complexity339
SMILES
CN1CCC(C1)CN2C3=CC=CC=C3SC4=CC=CC=C42
InChI
InChI=1S/C18H20N2S/c1-19-11-10-14(12-19)13-20-15-6-2-4-8-17(15)21-18-9-5-3-7-16(18)20/h2-9,14H,10-13H2,1H3
InChIKey
HTMIBDQKFHUPSX-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Methdilazine
CAS: 1982-37-2
CID: 14677
Formula: C18H20N2S
MW: 296.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight296.4
XLogP35.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass296.13471982
Monoisotopic Mass296.13471982
Topological Polar Surface Area31.8 Ų
Heavy Atom Count21
Formal Charge0
Complexity339
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
RM-M310000-01Methdilazine
MBS5782870Methdilazine Hydrochloride
HY-B1690A-01Methdilazine (hydrochloride)
HY-B1690ARMethdilazine (hydrochloride) (Standard)
sc-484752Methdilazine-d4 hydrochloride

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