CPD-10

• Target :

  Apoptosis|||PROTACs|||Glucocorticoid Receptor|||CDK

• Related Pathways :

  PROTAC|||Endocrinology/Hormones|||Apoptosis|||Cell Cycle/Checkpoint

• Bioactivity :

  CPD-10 is a potent bifunctional PROTAC degrader targeting CCND1 and CDK4 and exhibits antiproliferative effects. It induces apoptosis and reduces the protein expression of Cyclin D1, Cyclin D3, CDK4, and P-Rb (5807/811) in a dose-dependent manner.

• Smiles :

  O=C(NC1=NN=C(C=C1)N(C)C)C2=CC=C(N=C2NCCCCCCCNC(=O)CN3CCN(C4=CN=C(C=C4)NC=5N=CC6=C(N5)N(C(=O)C(C(=O)C)=C6C)C7CCCC7)CC3)NC

• Molecular Formula :

  C46H61N15O4

• Molecular Weight :

  888.08

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3055471-57-0