CPD-10

• Target:

  Apoptosis|||PROTACs|||Glucocorticoid Receptor|||CDK

• Related Pathways:

  PROTAC|||Endocrinology/Hormones|||Apoptosis|||Cell Cycle/Checkpoint

• Bioactivity:

  CPD-10 is a potent bifunctional PROTAC degrader targeting CCND1 and CDK4 and exhibits antiproliferative effects. It induces apoptosis and reduces the protein expression of Cyclin D1, Cyclin D3, CDK4, and P-Rb (5807/811) in a dose-dependent manner.

• Smiles:

  O=C (NC1=NN=C (C=C1) N (C) C) C2=CC=C (N=C2NCCCCCCCNC (=O) CN3CCN (C4=CN=C (C=C4) NC=5N=CC6=C (N5) N (C (=O) C (C (=O) C) =C6C) C7CCCC7) CC3) NC

• Molecular Formula:

  C46H61N15O4

• Molecular Weight:

  888.08

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3055471-57-0