DTAG-47

• Target :

  PROTACs|||FKBP

• Related Pathways :

  PROTAC|||Apoptosis|||Immunology/Inflammation|||Autophagy

• Bioactivity :

  DTAG-47, a heterobifunctional molecule, specifically targets the mutant FKBP12 (FKBP12 F36V), which functions as a degradation tag (dTAG) when fused to a protein of interest. This compound is utilized in the study of basal-like breast cancers (BBC) [1].

• Smiles :

  CC[C@H](C(=O)N1CCCC[C@H]1C(=O)O[C@H](CCc1ccc(OC)c(OC)c1)c1ccccc1OCC(=O)NCCCCCCCCNc1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1)c1cc(OC)c(OC)c(OC)c1

• Molecular Formula :

  C59H73N5O14

• Molecular Weight :

  1076.24

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2265886-81-3