EB-47

• Target:

  PARP

• Related Pathways:

  DNA Damage/DNA Repair|||Chromatin/Epigenetic

• Purity:

  0.9986

• Bioactivity:

  EB-47 mimics the substrate NAD+ and extends from the nicotinamide to the adenosine subsite.EB-47, a potent and selective PARP-1/ARTD-1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC50 value of 410 nM.

• Smiles:

  O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](C(=O)N4CCN(CC(NC5=C6C(C(=O)NC6)=CC=C5)=O)CC4)[C@H]1O

• Molecular Formula:

  C24H27N9O6

• Molecular Weight:

  537.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  366454-36-6