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ALK-IN-21

CAT: 0931-T74522-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T74522-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2901889-01-6
Target
Others, ALK
Related Pathways
Angiogenesis, Others, Tyrosine Kinase/Adaptors
Bioactivity
ALK-IN-21 (Compound B10), a proficient ALK inhibitor targeting the ALKG1202R mutation, demonstrates significant inhibitory activity with IC50 values of 4.59 nM against ALK WT, 2.07 nM against ALK L1196M, and 5.95 nM against ALK G1202R. Moreover, ALK-IN-21 effectively suppresses proliferation in ALK-positive Karpas299 and H2228 cells, achieving IC50 values of 0.07 μM. It is applicable for anaplastic large cell lymphoma research [1].
Molecular Formula
C35H45ClN6O6S4
Molecular Weight
809.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-146408ALK-IN-21
305587-01ALK

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