ALK-IN-22

CAT: 0931-MF-0062533-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0062533-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2468219-09-0
Target
Others|||Apoptosis|||ALK
Related Pathways
Angiogenesis|||Others|||Tyrosine Kinase/Adaptors|||Apoptosis
Bioactivity
ALK-IN-22 (compound I-24) is a potent ALK inhibitor with an IC50 of 2.3 nM for ALK, 3.7 nM for ALKL1196M, and 2.9 nM for ALKG1202R. It down-regulates phosphorylation of ALK and its downstream proteins, inducing apoptosis. ALK-IN-22 is suitable for studying tumors.
Smiles
C(N(C)C)(=O)C=1C=2C(=CC(NC=3N=C(NC4=C(C(NC)=O)C=CC=C4)C(Cl)=CN3)=CC2)NC1C
Molecular Formula
C24H24ClN7O2
Molecular Weight
477.95
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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MBS5805804ALK-IN-22
CR223-0.5mlALK

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