Bicuculline methochloride

• Target:

  GABA Receptor

• Related Pathways:

  Membrane transporter/Ion channel|||Neuroscience

• Purity:

  0.9935

• Bioactivity:

  Bicuculline methochloride is a competitive GABAA receptor antagonist and allosteric inhibitor with an IC50 of 1.7 ?M. It blocks Ca²?-dependent activation of potassium channels, exhibits convulsant activity, and is suitable for epilepsy research.

• Smiles:

  C[N+]1 (C) [C@] ([C@]2 (C3=C (C (=O) O2) C4=C (C=C3) OCO4) [H]) (C5=C (C=C6C (=C5) OCO6) CC1) [H].[Cl-]

• Molecular Formula:

  C21H20ClNO6

• Molecular Weight:

  417.84

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  38641-83-7