BCL6 PROTAC 1

• Target :

  Others|||PROTACs|||Bcl-6

• Related Pathways :

  Immunology/Inflammation|||Others|||PROTAC

• Bioactivity :

  BCL6 PROTAC 1 is a selective B-cell lymphoma 6 (BCL6) proteolysis targeting chimera (PROTAC) that inhibits the BCL6 cell reporter with an IC50 of 8.8 µM and significantly degrades BCL6 in diffuse large B-cell lymphoma (DLBCL) cell lines, making it valuable for tumor-related research [1].

• Smiles :

  [H][C@]12CN(CCN1c1ncc(Cl)c(Nc3cc4CCC(=O)N(C)c4c(OCCOC2)c3)n1)C(=O)CCC(=O)NCCCOCCOCCOc1cccc2C(=O)N([C@H]3CCC(=O)NC3=O)C(=O)c12

• Molecular Formula :

  C45H52ClN9O12

• Molecular Weight :

  946.4

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2257479-54-0