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BCL6 PROTAC 1

CAT: 0931-T73869-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T73869-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2257479-54-0
Target
Others, PROTACs, Bcl-6
Related Pathways
Immunology/Inflammation, Others, PROTAC
Bioactivity
BCL6 PROTAC 1 is a selective B-cell lymphoma 6 (BCL6) proteolysis targeting chimera (PROTAC) that inhibits the BCL6 cell reporter with an IC50 of 8.8 μM and significantly degrades BCL6 in diffuse large B-cell lymphoma (DLBCL) cell lines, making it valuable for tumor-related research [1].
Smiles
[H][C@]12CN(CCN1c1ncc(Cl)c(Nc3cc4CCC(=O)N(C)c4c(OCCOC2)c3)n1)C(=O)CCC(=O)NCCCOCCOCCOc1cccc2C(=O)N([C@H]3CCC(=O)NC3=O)C(=O)c12
Molecular Formula
C45H52ClN9O12
Molecular Weight
946.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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