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PROTAC Bcl2 degrader-1

CAT: 0931-T10485-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T10485-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2378801-85-3
Target
Bcl-2 Family, PROTACs
Related Pathways
PROTAC, Apoptosis
Bioactivity
PROTAC Bcl2 degrader-1 is a PROTAC, which potently and selectively induces the degradation of Mcl-1 (IC50: 11.81 μM) and Bcl-2 (IC50: 4.94 μM; DC50: 3.0 μM) .
Smiles
O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCOCCOCCNC(=O)CCCCC(=O)NCCN4C(=O)C5=CC=CC=6C(SC7=CC=C(Br)C=C7)=CC=C(C4=O)C56)C3C2=O)CC1
Molecular Formula
C45H45BrN6O10S
Molecular Weight
941.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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