Products for Research Use Only

BAY-3153

CAT: 0931-T73371-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T73371-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2771319-69-6
Target
CCR
Related Pathways
Immunology/Inflammation, GPCR/G Protein, Microbiology/Virology
Bioactivity
BAY-3153 is a selective CCR1 antagonist with species-specific potency values of human IC50 = 3 nM, rat IC50 = 11 nM, and mouse IC50 = 81 nM. BAY-3153 is used to investigate C-C motif chemokine receptor 1 signaling and its roles in inflammation, immune cell trafficking, and disease-associated chemokine responses.
Smiles
O(CC)C=1C=C(N2C3CN(C(=O)[C@@H]4N(C[C@@H](O)C4)C5=CC=C(Cl)C=C5)CC2COC3)C=CC1Cl
Molecular Formula
C25H29Cl2N3O4
Molecular Weight
506.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C