BAY-3153

• Target :

  CCR

• Related Pathways :

  Immunology/Inflammation|||GPCR/G Protein|||Microbiology/Virology

• Bioactivity :

  BAY-3153 is a selective CCR1 antagonist with species-specific potency values of human IC50 = 3 nM, rat IC50 = 11 nM, and mouse IC50 = 81 nM. BAY-3153 is used to investigate C-C motif chemokine receptor 1 signaling and its roles in inflammation, immune cell trafficking, and disease-associated chemokine responses.

• Smiles :

  O(CC)C=1C=C(N2C3CN(C(=O)[C@@H]4N(C[C@@H](O)C4)C5=CC=C(Cl)C=C5)CC2COC3)C=CC1Cl

• Molecular Formula :

  C25H29Cl2N3O4

• Molecular Weight :

  506.42

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2771319-69-6