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GSK3-IN-3

CAT: 0931-T73331-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T73331-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
331963-27-0
Target
Mitophagy, GSK-3
Related Pathways
PI3K/Akt/mTOR signaling, Stem Cells, Autophagy
Purity
0.9937
Bioactivity
GSK3-IN-3 is a mitochondrial autophagy (mitophagy) inducer and GSK-3 inhibitor (IC50: 3.01 μM) that induces parkin-dependent mitochondrial autophagy. GSK3-IN-3 is non-ATP and non-substrate competitive and neuroprotective against 6-OHDA.
Smiles
C(C)N1C=2C(C(O)=C(C(NNC(CCCCCCCCCCC)=O)=O)C1=O)=CC=CC2
Molecular Formula
C24H35N3O4
Molecular Weight
429.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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