FGFR-IN-9

• Target:

  Others|||FGFR

• Related Pathways:

  Angiogenesis|||Tyrosine Kinase/Adaptors|||Others

• Bioactivity:

  FGFR-IN-9 is a potent, reversible, and orally active inhibitor of the fibroblast growth factor receptor (FGFR) family, demonstrating IC50 values of 17.1 nM for FGFR4 WT, 29.6 nM for FGFR3, 30.7 nM for FGFR4 V550L, 46.7 nM for FGFR2, and 64.3 nM for FGFR1, respectively.

• Smiles:

  C[C@@H]1CN(C[C@@H](N1)C)C2=CC=C(C=C2)NC3=NC=C4C=CN(C4=N3)S(=O)(=O)C5=CC=CC(=C5)OC

• Molecular Formula:

  C25H28N6O3S

• Molecular Weight:

  492.59

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C