FGFR-IN-9

CAT: 0931-T73316-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T73316-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others|||FGFR
Related Pathways
Angiogenesis|||Tyrosine Kinase/Adaptors|||Others
Bioactivity
FGFR-IN-9 is a potent, reversible, and orally active inhibitor of the fibroblast growth factor receptor (FGFR) family, demonstrating IC50 values of 17.1 nM for FGFR4 WT, 29.6 nM for FGFR3, 30.7 nM for FGFR4 V550L, 46.7 nM for FGFR2, and 64.3 nM for FGFR1, respectively.
Smiles
C[C@@H]1CN(C[C@@H](N1)C)C2=CC=C(C=C2)NC3=NC=C4C=CN(C4=N3)S(=O)(=O)C5=CC=CC(=C5)OC
Molecular Formula
C25H28N6O3S
Molecular Weight
492.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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