RET-IN-13

CAT: 0931-T73248-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T73248-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2684258-54-4

Target

C-RET, Others

Related Pathways

Apoptosis, Others, Tyrosine Kinase/Adaptors

Bioactivity

RET-IN-13, a quinoline-based compound, effectively inhibits the RET kinase, demonstrating IC50 values of 0.5 nM for RET (WT) and 0.9 nM for RET (V804M) . It holds promise for research into tumors and intestinal diseases associated with abnormal RET activation.

Smiles

O(C)C1=CC2=C(C=C1OC)N=CC(=C2)C3=CC=C(CC(NC4=CC(C(F)(F)F)=C(CN5CCN(CC)CC5)C=C4F)=O)C=N3

Molecular Formula

C32H33F4N5O3

Molecular Weight

611.63

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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GTR19212278-01	RET-IN-13
R1701-17	RET protein (RET)
V8277-100UG	RET Antibody / c-RET
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332425-01	Ret

RET-IN-13

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