RET-IN-19

• Target :

  Others|||c-RET|||Aurora Kinase|||c-Fms|||MAPK|||EGFR

• Related Pathways :

  Chromatin/Epigenetic|||Apoptosis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Others|||MAPK|||Angiogenesis|||Cell Cycle/Checkpoint

• Bioactivity :

  RET-IN-19 is a potent inhibitor of RET and exhibits anticancer effects on RET-wt (IC50: 6.8 nM) and RET V804M (IC50: 13.51 nM) .RET-IN-19 can be used to study non-small cell lung cancer (NSCLC) .

• Smiles :

  N(C1=C2C(NC(=C2)C3=CC=C(S(C)(=O)=O)C=C3)=NC=N1)C4=CC=C(CC(NC=5C=C(C(C)(C)C)ON5)=O)C=C4

• Molecular Formula :

  C28H28N6O4S

• Molecular Weight :

  544.62

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2484919-71-1