EZH2-IN-14

CAT: 0931-MF-0146549-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0146549-01Size:25 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
1979157-17-9
Target
Histone Methyltransferase|||Others
Related Pathways
Chromatin/Epigenetic|||Others
Bioactivity
EZH2-IN-14 is a selective inhibitor of EZH2 (Histone Methyltransferase) with an IC50 value of 12 nM, targeting the methyltransferase activity of EZH2/PRC2 and reducing H3K27me3 levels. It exhibits more than 200-fold selectivity for EZH2 over the closely related H3K27 methyltransferase, EZH1.
Smiles
C(C)(C)N1C=2C(=C(C(NCC3=C(C)C=C(C)NC3=O)=O)C=C(C2)C=4C=CC(=NC4)N5CCN(C(C)C)CC5)C=N1
Molecular Formula
C31H39N7O2
Molecular Weight
541.69
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Popular Products