EZH2-IN-9

• Target:

  Histone Methyltransferase|||Others

• Related Pathways:

  Chromatin/Epigenetic|||Others

• Bioactivity:

  EZH2-IN-9 is a potent inhibitor of EZH2, which, through overexpression or mutations in the SET region (Y641F, Y641N, A687V, A677G point mutations), causes abnormal elevations in H3K27me3 and contributes to the growth and development of various tumours (e.g., breast cancer, prostate cancer, leukaemia) . EZH2-IN-9 has shown potential for cancer research.

• Smiles:

  CC1=C2C (OC (C) (O2) [C@@H]3CC[C@@H] (C (=O) N4CC (F) (F) C4) CC3) =C (Cl) C=C1C (NCC5=C (SC) C=C (C) NC5=O) =O

• Molecular Formula:

  C28H32ClF2N3O5S

• Molecular Weight:

  596.09

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2700897-24-9