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NLRP3-IN-14

CAT: 0931-T73013-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T73013-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2767369-80-0
Target
Others, NOD-like Receptor (NLR)
Related Pathways
Others, Immunology/Inflammation
Bioactivity
NLRP3-IN-14 is a potent, selective inhibitor of the NLRP3 inflammasome, displaying a dissociation constant (K D) of 5.87 μM and an IC50 of 0.131 μM for inhibiting IL-1β release. It is applicable for inflammation research.
Smiles
O=C1C(=O)C2=C(OC3=C2CCN(C3)CCCN4CCOCC4)C=5C=CC6=C(C=CC=C6C)C15
Molecular Formula
C27H28N2O4
Molecular Weight
444.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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