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Darizmetinib

CAT: 0931-T72956-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T72956-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2369583-33-3
Target
P38 MAPK, Antiviral, NF-κB, MDM-2/p53, JNK, MAPK
Related Pathways
NF-κB, Immunology/Inflammation, MAPK, Apoptosis
Purity
0.9957
Bioactivity
Darizmetinib (HRX215, HRX-0215) is an MKK4 inhibitor. Inhibition of MKK4 leads to enhancement of the MKK7 and JNK1 signaling pathways, thereby activating the transcription factors ATF2 and ELK1, promoting cell proliferation and liver regeneration.
Smiles
O=C(C1=NNC2=NC=C(C=C21)C=3C=CN=CC3)C4=CC=C(F)C(NS(=O)(=O)CCC)=C4F
Molecular Formula
C21H17F2N5O3S
Molecular Weight
457.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19219911-01Darizmetinib

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