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Darizmetinib

CAT: 0013-GTR19219911-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19219911-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Darizmetinib (HRX215) is a selective MKK4 inhibitor whose mechanism involves enhancing MKK7-JNK1 signaling to activate transcription factors like ATF2 and ELK1, thereby promoting hepatocyte proliferation. This activity supports its research use in studying liver regeneration and related disease models in both cellular and preclinical contexts.
CAS Number
2369583-33-3
Product Name Alternative
Antiviral, MAP2K, HRX-0215, HRX215
Field of Research
Cell Biology, Immunology & Inflammation, Signal Transduction
Purity
98.03% (May vary between batches)
Solubility
DMSO:180 mg/mL (393.49 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
O=C (C1=NNC2=NC=C (C=C21) C=3C=CN=CC3) C4=CC=C (F) C (NS (=O) (=O) CCC) =C4F
Molecular Formula
C21H17F2N5O3S
Molecular Weight
457.45
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
BA6516-1Darizmetinib

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