CDK4/6-IN-14

CAT: 0931-T72951-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T72951-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2699091-15-9

Target

Others, CDK

Related Pathways

Cell Cycle/Checkpoint, Others

Bioactivity

CDK4/6-IN-14 is a potent, highly selective inhibitor of Cyclin-Dependent Kinases 4 and 6 (CDK4/6), with inhibition concentrations (IC50s) of 10 nM and 16 nM, respectively. It shows over 60-fold selectivity for CDK4/6 compared to CDKs 1, 2, 7, and 9, and exhibits significant selectivity against 205 other kinases.

Smiles

Cl.O=C1C=2C=CC(=CC2CCN1CC)C3=NC(=NC=C3F)NC4=NC=C(C=C4)N5CCNCC5

Molecular Formula

C24H27ClFN7O

Molecular Weight

483.97

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
MBS5815191	CDK4/6-IN-14
MBS5785595	CDK4/6-IN-6
HY-168444	CDK4/6-IN-23
HY-162529	CDK4/6-IN-19
HY-114339-01	CDK4/6-IN-2
MBS5803058	CDK4/6-IN-12
MBS5804881	CDK4/6-IN-9
MBS5804586	CDK4/6-IN-8
GTR19230699-01	CDK4/6-IN-17
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CDK4/6-IN-14

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