E7766 disodium

• Target:

  Others|||STING

• Related Pathways:

  Immunology/Inflammation|||Others

• Bioactivity:

  E7766 disodium, a macrocycle-bridged STING agonist, exhibits a binding affinity (Kd) of 40 nM, demonstrating potent pan-genotypic and antitumor effects.

• Smiles:

  O=[P@@](OC[C@@H]1[C@@H](O2)[C@@H](F)[C@H]([N@@]3C=NC(C3=NC=N4)=C4NC/C=C/CN5)O1)(O[C@H]([C@H]6CO[P@@]2([S-])=O)[C@@H](F)[C@@H](O6)[N@]7C8=NC=NC5=C8N=C7)[S-].[Na+].[Na+]

• Molecular Formula:

  C24H26F2N10Na2O8P2S2

• Molecular Weight:

  792.58

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2242636-28-6