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P-gp inhibitor 4

CAT: 0931-T72678-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T72678-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2652001-05-1
Target
P-gp, Others
Related Pathways
Neuroscience, Others, Membrane transporter/Ion channel
Bioactivity
P-gp inhibitor 4 is a selective P-glycoprotein modulator with an EC 50 of 94 nM. P-gp inhibitor 4 increases drug transport across gastro-intestinal barrier and recovers doxorubicin toxicity in multidrug resistant cancer cells .
Smiles
N(S(=O)(=O)C1=CC=C(OC)C=C1)(S(=O)(=O)C2=CC=C(OC)C=C2)C3=CC=C(C=C3)C4=CC=C(CN5CC=6C(CC5)=CC(OC)=C(OC)C6)C=C4
Molecular Formula
C38H38N2O8S2
Molecular Weight
714.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C