Products for Research Use Only
RegisterLogin

Umbralisib sulfate

CAT: 0931-T72527-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T72527-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1532533-75-7
Target
Casein Kinase, Others, PI3K
Related Pathways
Others, Metabolism, PI3K/Akt/mTOR signaling, Stem Cells
Bioactivity
Umbralisib (TGR-1202) sulfate, an orally active compound, serves as a potent, selective inhibitor targeting both PI3Kδ and casein kinase-1-ε (CK1ε), with EC50 values of 22.2 nM and 6.0 μM, respectively. It demonstrates unique immunomodulatory effects on T cells in chronic lymphocytic leukemia (CLL) and is applicable in the research of hematological malignancies.
Smiles
S(=O)(=O)(O)O.NC1=C2C(=NN([C@@H](C)C3=C(C(=O)C=4C(O3)=CC=C(F)C4)C5=CC(F)=CC=C5)C2=NC=N1)C6=CC(F)=C(OC(C)C)C=C6
Molecular Formula
C31H26F3N5O7S
Molecular Weight
669.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T4976-01Umbralisib
T17066Umbralisib hydrochloride
T72465-01Umbralisib tosylate
T13140-01Umbralisib R-enantiomer
TXB-00492-01Dextran sulfate, low sulfate (MW 5000)
TXB-00493-01Dextran sulfate, low sulfate (MW 40000)
TXB-00494-01Dextran sulfate, high sulfate (MW 5000)
T32161-01Indoxyl sulfate
T77988Phenyl sulfate
T22455-01Vindesine sulfate

Alternative Products

CatalogName
HY-12279BUmbralisib (sulfate)
MBS5814888Umbralisib sulfate
205938Umbralisib
MBS5814848Umbralisib tosylate
GTR19203006Umbralisib hydrochloride
HY-12279R-01Umbralisib (Standard)
HY-12279AUmbralisib (tosylate)
HY-12279C-01Umbralisib (hydrochloride)
MBS5754038Umbralisib R-enantiomer
C13255-01Umbralisib (TGR-1202)

Popular Products