Products for Research Use Only

AZ13705339 hemihydrate

CAT: 0931-T72321-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T72321-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PAK, Others
Related Pathways
Cytoskeletal Signaling, Others
Bioactivity
AZ13705339 hemihydrate is a hemihydrate form of AZ13705339, exhibiting high potency and selectivity as a PAK1 inhibitor, demonstrating IC50 values of 0.33 nM for PAK1 and 59 nM for pPAK1. It also shows strong binding affinities with Kd values of 0.28 nM for PAK1 and 0.32 nM for PAK2. This compound is utilized in cancer research.
Smiles
CCS(=O)(C1=C(N2CCN(C)CC2)C=CC(NC3=NC=C(F)C(N(C4=C(C)C=CC(CO)=C4)CC5=CC=CC=C5C#N)=N3)=C1)=O.CCS(=O)(C6=C(N7CCN(C)CC7)C=CC(NC8=NC=C(F)C(N(C9=C(C)C=CC(CO)=C9)CC%10=CC=CC=C%10C#N)=N8)=C6)=O.O
Molecular Formula
C33H36FN7O3S.1/2H2O
Molecular Weight
638.77
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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