Products for Research Use Only

Isonanangenine B

CAT: 0931-T71925-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T71925-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1623153-14-9
Target
Others
Related Pathways
Others
Bioactivity
Isonanangenine B is a drimane sesquiterpene lactone that has been found in Aspergillus. It decreases survivin mRNA expression in a reporter assay when used at concentrations of 13.6, 18.42, and 26.31 μM. Isonanagenine B (18.42 μM) inhibits STAT3 and NF-κB binding to the survivin promoter in chromatin immunoprecipitation (ChIP) assays. It also induces apoptosis in COLO 320DM cells.
Smiles
[H][C@@]12[C@H](OC(=O)CCCCC)C=C3C(=O)OC[C@]3(O)[C@@]1(C)[C@H](O)CCC2(C)C
Molecular Formula
C21H32O6
Molecular Weight
380.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products