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AEZS-112

CAT: 0931-T71218-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T71218-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1214741-69-1
Target
Others
Related Pathways
Others
Bioactivity
AEZS-112, also known as ZEN012, is an orally active small mol. anti-cancer drug which inhibits the polymn. of tubulin at low micromolar concns. AEZS 112 dose-dependently increased non-vital hypodiploid cells and the cytotoxic effect was least pronounced in G2 phase of the cell cycle, indicating cell death during mitosis, as detd. by FACS anal. AEZS 112 showed anti-tumor activity in human ovarian and endometrial cancer cell lines at low micromolar concns., which could not be abrogated by caspase inhibition and is therefore a good candidate for in vivo studies in these tumors.
Molecular Formula
C25H23N3O2
Molecular Weight
397.46902
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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MBS5813757AEZS-112
A13536-50AEZS-108 50mg
A13536-25AEZS-108 25mg
A13536-5AEZS-108 5mg
A13536-10AEZS-108 10mg
A13536-100AEZS-108 100mg
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