Racecadotril-d5

• Target:

  Neprilysin

• Related Pathways:

  Metabolism

• Bioactivity:

  Racecadotril-d5 is intended for use as an internal standard for the quantification of racecadotril by GC- or LC-MS. Racecadotril is a prodrug form of the neprilysin (NEP) inhibitor thiorphan. In vivo, racecadotril reduces or prevents castor oil-induced diarrhea without delaying intestinal transit in rats when administered at doses of 80 or 100 mg/kg, respectively. It also decreases the duration of diarrhea and increases body weight gain in a neonatal gnotobiotic pig model of human rotavirus-induced diarrhea. Formulations containing racecadotril have been used in the treatment of acute diarrhea.

• Smiles:

  C (CC1=CC=CC=C1) (C (NCC (OCC2=C (C (=C (C (=C2[2H]) [2H]) [2H]) [2H]) [2H]) =O) =O) CSC (C) =O

• Molecular Formula:

  C21H18D5NO4S

• Molecular Weight:

  390.51

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1246815-11-1