TLR9-IN-18

CAT: 0931-T70905-01Size: 25 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T70905-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

1351978-48-7

Target

Others

Related Pathways

Others

Bioactivity

TLR9-IN-18 is a potent and selective TLR9 antagonist. TLR9-IN-18 suppresses the production of the proinflammatory cytokine IL-6 in a CpG-induced mouse model.

Smiles

C(CCN1CCOCC1)N2C=3C(=CN=C(N3)C4=CC=C(C=C4)N5CCN(CCO)CC5)CC2

Molecular Formula

C25H36N6O2

Molecular Weight

452.59

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

2-[4-[4-[7-(3-Morpholin-4-ylpropyl)-5,6-dihydropyrrolo[2,3-d]pyrimidin-2-yl]phenyl]piperazin-1-yl]ethanol

CAS Number	1351978-48-7
PubChem CID	54760856
IUPAC Name	2-[4-[4-[7-(3-morpholin-4-ylpropyl)-5,6-dihydropyrrolo[2,3-d]pyrimidin-2-yl]phenyl]piperazin-1-yl]ethanol
Molecular Formula	C25H36N6O2
Molecular Weight	452.6
XLogP	1.6
Topological Polar Surface Area	68.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	8
Heavy Atom Count	33
Formal Charge	0
Complexity	575

SMILES

C1CN(C2=NC(=NC=C21)C3=CC=C(C=C3)N4CCN(CC4)CCO)CCCN5CCOCC5

InChI

InChI=1S/C25H36N6O2/c32-17-14-29-10-12-30(13-11-29)23-4-2-21(3-5-23)24-26-20-22-6-9-31(25(22)27-24)8-1-7-28-15-18-33-19-16-28/h2-5,20,32H,1,6-19H2

InChIKey

VQQGQCSLCPMKAG-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1351978-48-7

CID: 54760856

Formula: C25H36N6O2

MW: 452.6

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	452.6
XLogP3	1.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	8
Exact Mass	452.28997441
Monoisotopic Mass	452.28997441
Topological Polar Surface Area	68.2 Å²
Heavy Atom Count	33
Formal Charge	0
Complexity	575
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
T62254	TLR9-IN-1
T209088-01	TLR7 agonist 18
TMAB-13576-01	Anti-TLR9 Antibody (6N996)
TMAB-01861-01	Anti-TLR9 Polyclonal Antibody
TMID-0178-01	Stearic acid-18,18,18-d3
TMAB-01862-01	Anti-TLR9 Polyclonal Antibody 2
T31040	CP-18 F-18
TCL-00013-01	18:0-18:2 PE
T205670-01	18:0-18:2 PG sodium
T205426-01	18:0-18:1 PA sodium

Alternative Products

Catalog	Name
MBS5813447	TLR9-IN-18
MBS8535198-01	TLR9
BA6293-5	TLR9-IN-1
70R-5952	TLR9 antibody
531928-01	TLR9 discontinued
579130-01	TLR9 (HRP)
MBS152758-01	TLR9 Peptide
RA25070	TLR9/CD289

TLR9-IN-18

Chemical Information

Related Products

Alternative Products

Popular Products