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GW-841819X

CAT: 0931-T70593-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T70593-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
146135-18-4
Target
Epigenetic Reader Domain, Others
Related Pathways
Chromatin/Epigenetic, Others
Bioactivity
GW841819X is an analogue of (+) -JQ1 and a novel inhibitor of BET bromodomains. GW841819X displayed activity in vivo against NUT-midline carcinoma, multiple myeloma, mixed-lineage leukemia, and acute myeloid leukemia. Bromodomain and extra-terminal (BET) proteins belong to a class of proteins collectively called epigenetic readers". BET bromodomains have emerged as promising drug targets for treatment of cancers
Smiles
CC=1N2C=3C(C(=NC(NC(OCC4=CC=CC=C4)=O)C2=NN1)C5=CC=CC=C5)=CC=CC3
Molecular Formula
C25H21N5O2
Molecular Weight
423.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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