GW-3333

• Target :

  Others|||MMP|||TNF

• Related Pathways :

  Apoptosis|||Proteases/Proteasome|||Others

• Bioactivity :

  GW-3333 is an matrix metalloproteinase inhibitor. It is also a tumor necrosis factor-alpha (TNF) -Converting Enzyme (TACE) inhibitor. The efficacy of GW3333 suggests that dual inhibitors of matrix metalloproteinases and TACE may prove therapeutic as antiarthritics.

• Smiles :

  [C@@H]([C@@H](N(C=O)O)C(C)C)(C(N[C@H](C(NC1=CC=CC=N1)=O)[C@H](CC)C)=O)CC(C)C

• Molecular Formula :

  C22H36N4O4

• Molecular Weight :

  420.55

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  212609-68-2