GW-3333

• Target:

  Others|||MMP|||TNF

• Related Pathways:

  Apoptosis|||Proteases/Proteasome|||Others

• Bioactivity:

  GW-3333 is an matrix metalloproteinase inhibitor. It is also a tumor necrosis factor-alpha (TNF) -Converting Enzyme (TACE) inhibitor. The efficacy of GW3333 suggests that dual inhibitors of matrix metalloproteinases and TACE may prove therapeutic as antiarthritics.

• Smiles:

  [C@@H] ([C@@H] (N (C=O) O) C (C) C) (C (N[C@H] (C (NC1=CC=CC=N1) =O) [C@H] (CC) C) =O) CC (C) C

• Molecular Formula:

  C22H36N4O4

• Molecular Weight:

  420.55

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  212609-68-2