Amonafide dihydrochloride

CAT: 0931-MF-0065700-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0065700-01Size:25 mg
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CAS Number
150091-68-2
Target
Others|||Topoisomerase
Related Pathways
Others|||DNA Damage/DNA Repair
Bioactivity
Amonafide dihydrochloride is the dihydrochloride salt of amonafide, an imide derivative of naphthalic acid. Amonafide intercalates into DNA and inhibits topoisomerase II, resulting in protein-associated strand breaks and impaired DNA and RNA synthesis.
Smiles
Cl.Cl.CN(C)CCN1C(=O)c2cccc3cc(N)cc(C1=O)c23
Molecular Formula
C16H19Cl2N3O2
Molecular Weight
283.32508
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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