KB-R7785

• Target:

  Others|||MMP

• Related Pathways:

  Proteases/Proteasome|||Others

• Bioactivity:

  KB-R7785 is a novel ADAM12 and MMP inhibitor, ameliorating cardiac function in a transverse aortic constriction (TAC) model by inhibiting the proteolytic activation of HB-EGF signaling, exerting its antidiabetic effect by ameliorating insulin sensitivity through the inhibition of TNF-alpha production.

• Smiles:

  [C@@H](NC([C@@H]([C@@H](C(NO)=O)C)CC(C)C)=O)(C(NC)=O)C1=CC=CC=C1

• Molecular Formula:

  C18H27N3O4

• Molecular Weight:

  349.42

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  168158-16-5