Chlorhexidine-d8 HCl

CAT: 0931-MF-0098446Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0098446Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2012598-75-1
Target
Antibacterial|||Antibiotic
Related Pathways
Microbiology/Virology
Bioactivity
Chlorhexidine-d8 is intended for use as an internal standard for the quantification of chlorhexidine by GC- or LC-MS. Chlorhexidine is a bis (biguanide) antimicrobial disinfectant and antiseptic agent. It inhibits growth of clinical methicillin-resistant S. aureus (MRSA) isolates (MIC90 = 4 ?g/ml) . It is also active against canine isolates of MRSA, methicillin-susceptible S. aureus (MSSA), methicillin-resistant S. pseudintermedius (MRSP), and methicillin-susceptible S. pseudintermedius (MSSP; MIC90s = 4, 2, 2, and 1 mg/L, respectively) . Chlorhexidine inhibits growth of E. faecium strains (MICs = 1.2-19.6 ?g/ml) and C. albicans (MIC = 5.15 ?g/ml) . It generates cations that bind to and destabilize the bacterial cell wall to induce death.6 Chlorhexidine also completely inhibits matrix metalloproteinase-2 (MMP-2) and MMP-9 when used at concentrations of 0.0001 and 0.002%, respectively, in a gelatin degradation assay. Formulations containing chlorhexidine have been used in antisept......
Smiles
Cl.Cl.[2H]c1c([2H])c(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2c([2H])c([2H])c(Cl)c([2H])c2[2H])c([2H])c([2H])c1Cl
Molecular Formula
C22H24D8Cl4N10
Molecular Weight
586.4168
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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