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Delgocitinib EtOH

CAT: 0931-T69950-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T69950-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2064338-33-4
Target
Others, JAK
Related Pathways
Angiogenesis, JAK/STAT signaling, Stem Cells, Others, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors
Bioactivity
Delgocitinib, also known as LEO-124249 and JTE052, is a potent and selective JAK inhibitor. JTE-052 reduces skin inflammation and ameliorates chronic dermatitis in rodent models: Comparison with conventional therapeutic agents. JTE-052 regulates contact hypersensitivity by downmodulating T cell activation and differentiation.
Smiles
CCO.C[C@H]1CN(C(=O)CC#N)[C@]11CCN(C1)c1ncnc2[nH]ccc12
Molecular Formula
C18H24N6O2
Molecular Weight
356.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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