TSI-13-57

• Target:

  MyD88|||TNF

• Related Pathways:

  Immunology/Inflammation|||Apoptosis

• Purity:

  0.9963

• Bioactivity:

  TSI-13-57 is a MyD88 inhibitor or pan-TLR inhibitor that suppresses MyD88 TIR domain dimerization without affecting MyD88-receptor interactions. TSI-13-57 inhibits LPS-induced TNF-? (IC50 = 6.73 mM) .

• Smiles:

  OC1=CC=C(C=2N(N=C(C2)C3=CC=C(OCCN4CCCCC4)C=C3)C5=CC=C(O)C=C5)C=C1

• Molecular Formula:

  C28H29N3O3

• Molecular Weight:

  455.55

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2257427-45-3